NEJM -- Intensive versus Conventional Glucose Control in Critically Ill Patients: "Intensive versus Conventional Glucose Control in Critically Ill Patients
The NICE-SUGAR Study Investigators"
Conclusions In this large, international, randomized trial, we found that intensive glucose control increased mortality among adults in the ICU: a blood glucose target of 180 mg or less per deciliter resulted in lower mortality than did a target of 81 to 108 mg per deciliter. (ClinicalTrials.gov number, NCT00220987 [ClinicalTrials.gov] .)
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